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bezafibrate and (3S,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid

bezafibrate has been researched along with (3S,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's12 (54.55)18.2507
2000's9 (40.91)29.6817
2010's1 (4.55)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Espinosa, J; Fanghänel, G; Hernández, G; Macías, G; Martínez, L; Morales, M; Olivares, D; Sánchez, L; Valdés, E1
Eliav, O; Friedlander, Y; Leitersdorf, E; Pfister, P; Schurr, D1
Eliav, O; Leitersdorf, E; Muratti, EN; Peters, TK1
Armstrong, VW; Beil, FU; Eskötter, H; Greten, H; Keller, C; Klör, HU; Schneider, J; von Hodenberg, E; Weidinger, G; Weisweiler, P1
Dann, EJ; Eisenberg, S; Eliav, O; Leitersdorf, E; Meiner, V; Muratti, EN; Peters, TK; Sehayek, E; Stein, Y1
Leitersdorf, E; Muratti, EN; Peters, TK1
Jokubaitis, LA1
Eagles, CJ; Kendall, MJ; Maxwell, S1
Hailer, S; Keller, C; Pogarell, O; Wolfram, G1
Eagles, CJ; Kendall, MJ1
Ganotakis, ES; Jagroop, IA; Mikhailidis, DP; Papadakis, JA; Winder, AF1
Hemsley, D; Wray, R1
Hannak, M; Lüscher, TF; Noll, G; Spieker, LE1
Boschetti, C; Cofrancesco, E; Cortellaro, F; Cortellaro, M; Mancini, M; Mariani, M; Paoletti, R1
Borgnino, C; Mancini, M; Mariani, M; Paoletti, R; Pauciullo, P1
Hirschfield, G1
Akahane, M; Aoyagi, S; Awata, T; Hayashi, K; Inoue, I; Itoh, F; Katayama, S; Komoda, T; Kusama, H; Mastunaga, T; Tazawa, S1
Bortolini, M; Farnier, M; Freudenreich, MO; Gonasun, L; Isaacsohn, JL; Salko, T; Troendle, AJ1
Dejager, S; Farnier, M; Gonasun, L; Isaacsohn, JL; Salko, T; Troendle, AJ1
Balice, M; Chironi, G; Del-Pino, M; Gariepy, J; Levenson, J; Simon, A1
Hidaka, H; Hongo, M; Ikeda, U; Kinoshita, O; Kumazaki, S; Mawatari, E; Takahashi, M; Tsutsui, H; Yazaki, Y1
Hohendorff, B; Mühldorfer-Fodor, M; Prommersberger, KJ; Schmitt, R; Wagner, M1

Reviews

1 review(s) available for bezafibrate and (3S,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid

ArticleYear
Fluvastatin in combination with other lipid-lowering agents.
    British journal of clinical practice. Supplement, 1996, Volume: 77A

    Topics: Anticholesteremic Agents; Bezafibrate; Cholesterol, HDL; Cholesterol, LDL; Cholestyramine Resin; Drug Therapy, Combination; Fatty Acids, Monounsaturated; Fluvastatin; Humans; Hypercholesterolemia; Hypolipidemic Agents; Indoles; Niacin; Randomized Controlled Trials as Topic

1996

Trials

14 trial(s) available for bezafibrate and (3S,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid

ArticleYear
Open-label study to assess the efficacy, safety, and tolerability of fluvastatin versus bezafibrate for hypercholesterolemia.
    The American journal of cardiology, 1995, Jul-13, Volume: 76, Issue:2

    Topics: Adult; Aged; Anticholesteremic Agents; Bezafibrate; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Drug Tolerance; Fatty Acids, Monounsaturated; Female; Fluvastatin; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Male; Middle Aged; Safety; Triglycerides

1995
High-dose fluvastatin and bezafibrate combination treatment for heterozygous familial hypercholesterolemia.
    The American journal of cardiology, 1995, Jul-13, Volume: 76, Issue:2

    Topics: Anticholesteremic Agents; Bezafibrate; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cholestyramine Resin; Delayed-Action Preparations; Drug Combinations; Fatty Acids, Monounsaturated; Fluvastatin; Heterozygote; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipoproteinemia Type II; Indoles; Kidney; Liver; Longitudinal Studies; Placebos; Safety; Triglycerides

1995
Efficacy and safety of triple therapy (fluvastatin-bezafibrate-cholestyramine) for severe familial hypercholesterolemia.
    The American journal of cardiology, 1995, Jul-13, Volume: 76, Issue:2

    Topics: Adult; Anticholesteremic Agents; Bezafibrate; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cholestyramine Resin; Coronary Artery Disease; Creatine Kinase; Drug Combinations; Fatty Acids, Monounsaturated; Female; Fluvastatin; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipoproteinemia Type II; Indoles; Kidney; Liver; Male; Middle Aged; Patient Compliance; Placebos; Safety; Triglycerides

1995
Treatment of primary hypercholesterolemia: fluvastatin versus bezafibrate.
    The American journal of medicine, 1994, Jun-06, Volume: 96, Issue:6A

    Topics: Adult; Aged; Analysis of Variance; Anticholesteremic Agents; Bezafibrate; Double-Blind Method; Fatty Acids, Monounsaturated; Female; Fluvastatin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Lipids; Male; Middle Aged; Treatment Outcome

1994
Efficacy and safety of a combination fluvastatin-bezafibrate treatment for familial hypercholesterolemia: comparative analysis with a fluvastatin-cholestyramine combination.
    The American journal of medicine, 1994, Volume: 96, Issue:5

    Topics: Adult; Aged; Anticholesteremic Agents; Bezafibrate; Cholesterol, HDL; Cholesterol, LDL; Cholestyramine Resin; Double-Blind Method; Drug Combinations; Fatty Acids, Monounsaturated; Female; Fluvastatin; Heterozygote; Humans; Hyperlipoproteinemia Type II; Indoles; Male; Middle Aged; Myositis; Placebos; Safety; Single-Blind Method; Triglycerides

1994
Fluvastatin in familial hypercholesterolemia: a cohort analysis of the response to combination treatment.
    The American journal of cardiology, 1994, May-26, Volume: 73, Issue:14

    Topics: Adult; Analysis of Variance; Anticholesteremic Agents; Bezafibrate; Cholestyramine Resin; Cohort Studies; Double-Blind Method; Drug Therapy, Combination; Drug Tolerance; Fatty Acids, Monounsaturated; Female; Fluvastatin; Heterozygote; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipoproteinemia Type II; Indoles; Lipids; Lipoproteins; Male; Middle Aged; Retrospective Studies; Time Factors

1994
Fluvastatin in combination with other lipid-lowering agents.
    British journal of clinical practice. Supplement, 1996, Volume: 77A

    Topics: Anticholesteremic Agents; Bezafibrate; Cholesterol, HDL; Cholesterol, LDL; Cholestyramine Resin; Drug Therapy, Combination; Fatty Acids, Monounsaturated; Fluvastatin; Humans; Hypercholesterolemia; Hypolipidemic Agents; Indoles; Niacin; Randomized Controlled Trials as Topic

1996
A comparison of the effects of fluvastatin and bezafibrate on exercise metabolism: a placebo-controlled study in healthy normolipidaemic subjects.
    British journal of clinical pharmacology, 1996, Volume: 41, Issue:5

    Topics: Adult; Analysis of Variance; Bezafibrate; Cross-Over Studies; Double-Blind Method; Energy Metabolism; Exercise; Fatty Acids, Monounsaturated; Fatty Acids, Nonesterified; Female; Fluvastatin; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Indoles; Male; Oxidation-Reduction

1996
Effect of fluvastatin or bezafibrate on the distribution of high density lipoprotein subpopulations in patients with familial hypercholesterolemia.
    Arzneimittel-Forschung, 1996, Volume: 46, Issue:9

    Topics: Adult; Aged; Anticholesteremic Agents; Bezafibrate; Blood Protein Electrophoresis; Fatty Acids, Monounsaturated; Female; Fluvastatin; Humans; Hyperlipoproteinemia Type II; Hypolipidemic Agents; Indoles; Lipoproteins, HDL; Male; Middle Aged

1996
The effects of combined treatment with beta 1-selective receptor antagonists and lipid-lowering drugs on fat metabolism and measures of fatigue during moderate intensity exercise: a placebo-controlled study in healthy subjects.
    British journal of clinical pharmacology, 1997, Volume: 43, Issue:3

    Topics: Adrenergic beta-Antagonists; Adult; Ammonia; Analysis of Variance; Anticholesteremic Agents; Atenolol; Bezafibrate; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Energy Metabolism; Exercise; Fatigue; Fatty Acids, Monounsaturated; Fatty Acids, Nonesterified; Female; Fluvastatin; Heart Rate; Humans; Hypolipidemic Agents; Indoles; Lactic Acid; Lipids; Male; Oxygen Consumption; Triglycerides

1997
Efficacy and tolerability of fluvastatin and bezafibrate in patients with hyperlipidemia and persistently high triglyceride levels.
    Journal of cardiovascular pharmacology, 2000, Volume: 35, Issue:3

    Topics: Adult; Aged; Bezafibrate; Cholesterol; Double-Blind Method; Drug Therapy, Combination; Fatty Acids, Monounsaturated; Female; Fluvastatin; Hemodynamics; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Hypertriglyceridemia; Hypolipidemic Agents; Indoles; Male; Middle Aged

2000
Effects of fluvastatin and bezafibrate combination on plasma fibrinogen, t-plasminogen activator inhibitor and C reactive protein levels in coronary artery disease patients with mixed hyperlipidaemia (FACT study). Fluvastatin Alone and in Combination Trea
    Thrombosis and haemostasis, 2000, Volume: 83, Issue:4

    Topics: Adult; Aged; Bezafibrate; C-Reactive Protein; Cholesterol, LDL; Coronary Disease; Double-Blind Method; Drug Synergism; Drug Therapy, Combination; Fatty Acids, Monounsaturated; Female; Fibrinogen; Fluvastatin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemia, Familial Combined; Hyperlipoproteinemia Type II; Hypertriglyceridemia; Hypolipidemic Agents; Indoles; Male; Middle Aged; Tissue Plasminogen Activator; Treatment Outcome

2000
Efficacy and safety of a combination of fluvastatin and bezafibrate in patients with mixed hyperlipidaemia (FACT study).
    Atherosclerosis, 2000, Volume: 150, Issue:2

    Topics: Adult; Aged; Bezafibrate; Biomarkers; Cholesterol, HDL; Cholesterol, LDL; Double-Blind Method; Drug Therapy, Combination; Fatty Acids, Monounsaturated; Female; Fluvastatin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipoproteinemia Type V; Hypolipidemic Agents; Indoles; Male; Middle Aged; Safety; Treatment Outcome; Triglycerides

2000
Fluvastatin improves arterial stiffness in patients with coronary artery disease and hyperlipidemia: a 5-year follow-up study.
    Circulation journal : official journal of the Japanese Circulation Society, 2008, Volume: 72, Issue:5

    Topics: Aged; Aorta; Bezafibrate; Blood Flow Velocity; Coronary Artery Disease; Fatty Acids, Monounsaturated; Female; Fluvastatin; Follow-Up Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Hypolipidemic Agents; Indoles; Linear Models; Male; Middle Aged; Multivariate Analysis; Prospective Studies; Pulsatile Flow; Risk Factors; Treatment Outcome

2008

Other Studies

8 other study(ies) available for bezafibrate and (3S,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid

ArticleYear
Statin + fibrate combination therapy fluvastatin with bezafibrate or ciprofibrate in high risk patients with vascular disease.
    International journal of cardiology, 1999, Jun-01, Volume: 69, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Anticholesteremic Agents; Bezafibrate; Cardiovascular Diseases; Clofibric Acid; Drug Therapy, Combination; Fatty Acids, Monounsaturated; Female; Fibric Acids; Fluvastatin; Humans; Hyperlipidemias; Hypolipidemic Agents; Indoles; Male; Middle Aged; Pilot Projects; Treatment Outcome

1999
Statin + fibrate combination therapy--fluvastatin with bezafibrate or ciprofibrate in high risk patients with vascular disease.
    International journal of cardiology, 1999, Dec-01, Volume: 71, Issue:3

    Topics: Bezafibrate; Cholesterol; Drug Synergism; Drug Therapy, Combination; Fatty Acids, Monounsaturated; Fluvastatin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Indoles; Treatment Outcome; Triglycerides; Vascular Diseases

1999
Effects of fluvastatin and bezafibrate combination on plasma fibrinogen, t-plasminogen activator inhibitor and C reactive protein levels in coronary artery disease patients with mixed hyperlipidaemia (FACT Study)--a rebuttal.
    Thrombosis and haemostasis, 2001, Volume: 85, Issue:1

    Topics: Bezafibrate; C-Reactive Protein; Coronary Disease; Drug Therapy, Combination; Fatty Acids, Monounsaturated; Fluvastatin; Humans; Hyperlipidemias; Hypolipidemic Agents; Indoles; Models, Statistical

2001
Fibrate and statin synergistically increase the transcriptional activities of PPARalpha/RXRalpha and decrease the transactivation of NFkappaB.
    Biochemical and biophysical research communications, 2002, Jan-11, Volume: 290, Issue:1

    Topics: Anticholesteremic Agents; Bezafibrate; Blotting, Western; CCAAT-Enhancer-Binding Proteins; Cell Nucleus; DNA-Binding Proteins; DNA, Complementary; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Fatty Acids, Monounsaturated; Fluvastatin; Gene Library; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Indoles; Ligands; Liver; Mitogen-Activated Protein Kinase Kinases; Models, Biological; Muscle, Skeletal; NF-kappa B; Nuclear Proteins; Protein Structure, Tertiary; Pyridines; Quinolines; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Recombinant Fusion Proteins; Retinoid X Receptors; Sequence Analysis, DNA; Sterol Regulatory Element Binding Protein 1; Trans-Activators; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transfection

2002
Frequency of creatine kinase elevation during treatment with fluvastatin in combination with fibrates (bezafibrate, fenofibrate, or gemfibrozil).
    The American journal of cardiology, 2003, Jan-15, Volume: 91, Issue:2

    Topics: Adult; Bezafibrate; Creatine Kinase; Drug Therapy, Combination; Fatty Acids, Monounsaturated; Female; Fenofibrate; Fluvastatin; Gemfibrozil; Humans; Hypercholesterolemia; Hyperlipidemias; Hypolipidemic Agents; Indoles; Male; Middle Aged

2003
Effects of baseline level of triglycerides on changes in lipid levels from combined fluvastatin + fibrate (bezafibrate, fenofibrate, or gemfibrozil).
    The American journal of cardiology, 2003, Oct-01, Volume: 92, Issue:7

    Topics: Age Factors; Bezafibrate; Drug Combinations; Fatty Acids, Monounsaturated; Female; Fenofibrate; Fluvastatin; Gemfibrozil; Humans; Hyperlipidemias; Hypolipidemic Agents; Indoles; Lipid Metabolism; Lipoproteins; Male; Middle Aged; Retrospective Studies; Sex Factors; Treatment Outcome; Triglycerides

2003
Differential associations of statin and fibrate treatment with carotid arterial remodeling.
    American journal of hypertension, 2005, Volume: 18, Issue:11

    Topics: Adult; Atorvastatin; Bezafibrate; Body Mass Index; Carotid Arteries; Cholesterol, HDL; Clofibric Acid; Cohort Studies; Dyslipidemias; Fatty Acids, Monounsaturated; Female; Fenofibrate; Fibric Acids; Fluvastatin; Gemfibrozil; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Indoles; Male; Middle Aged; Multivariate Analysis; Pravastatin; Pyridines; Pyrroles; Risk Factors; Simvastatin; Treatment Outcome; Tunica Intima; Tunica Media; Ultrasonography

2005
[Focal myositis as a side effect of antilipidemics - 2 patients with involvement of the forearm].
    Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Mikrochirurgie der Peripheren Nerven und Gefasse : Organ der V..., 2012, Volume: 44, Issue:1

    Topics: Anticholesteremic Agents; Atorvastatin; Bezafibrate; Coronary Disease; Drug Therapy, Combination; Fatty Acids, Monounsaturated; Female; Fluvastatin; Follow-Up Studies; Forearm; Heptanoic Acids; Humans; Hyperlipidemias; Image Interpretation, Computer-Assisted; Indoles; Magnetic Resonance Imaging; Male; Middle Aged; Muscle, Skeletal; Myositis; Pyrroles

2012